| Round of 16 — Direct Qualification | ||||||||||
| 1 | Benfica | 8 | 7 | 1 | 0 | 25 | 6 | +19 | 22 | Direct |
| 2 | Liverpool | 8 | 7 | 1 | 0 | 21 | 5 | +16 | 22 | Direct |
| 3 | Chelsea | 8 | 7 | 0 | 1 | 32 | 7 | +25 | 21 | Direct |
| 4 | Arsenal | 8 | 6 | 1 | 1 | 23 | 6 | +17 | 19 | Direct |
| 5 | Real Madrid | 8 | 6 | 1 | 1 | 23 | 6 | +17 | 19 | Direct |
| 6 | Juventus | 8 | 5 | 2 | 1 | 19 | 5 | +14 | 17 | Direct |
| 7 | Paris SG | 8 | 5 | 2 | 1 | 21 | 8 | +13 | 17 | Direct |
| 8 | Fenerbahce | 8 | 5 | 2 | 1 | 21 | 12 | +9 | 17 | Direct |
| Knockout Playoff Round | ||||||||||
| 9 | RB Leipzig | 8 | 4 | 3 | 1 | 14 | 9 | +5 | 15 | Playoff |
| 10 | PSV Eindhoven | 8 | 4 | 2 | 2 | 11 | 12 | -1 | 14 | Playoff |
| 11 | Celtic | 8 | 4 | 1 | 3 | 20 | 15 | +5 | 13 | Playoff |
| 12 | Porto | 8 | 4 | 1 | 3 | 15 | 14 | +1 | 13 | Playoff |
| 13 | Borussia Dortmund | 8 | 4 | 1 | 3 | 13 | 13 | 0 | 13 | Playoff |
| 14 | Barcelona | 8 | 3 | 3 | 2 | 13 | 6 | +7 | 12 | Playoff |
| 15 | Galatasaray | 8 | 3 | 3 | 2 | 13 | 10 | +3 | 12 | Playoff |
| 16 | Standard Liege | 8 | 4 | 0 | 4 | 19 | 18 | +1 | 12 | Playoff |
| 17 | Maccabi Tel Aviv | 8 | 4 | 0 | 4 | 12 | 12 | 0 | 12 | Playoff |
| 18 | AC Milan | 8 | 4 | 0 | 4 | 18 | 20 | -2 | 12 | Playoff |
| 19 | Basel | 8 | 3 | 3 | 2 | 10 | 12 | -2 | 12 | Playoff |
| 20 | Olympiacos | 8 | 3 | 1 | 4 | 16 | 14 | +2 | 10 | Playoff |
| 21 | Ajax | 8 | 3 | 1 | 4 | 14 | 14 | 0 | 10 | Playoff |
| 22 | Shakhtar Donetsk | 8 | 3 | 1 | 4 | 12 | 14 | -2 | 10 | Playoff |
| 23 | Red Bull Salzburg | 8 | 2 | 3 | 3 | 13 | 16 | -3 | 9 | Playoff |
| 24 | Young Boys | 8 | 1 | 5 | 2 | 8 | 13 | -5 | 8 | Playoff |
| Eliminated | ||||||||||
| 25 | Manchester City | 8 | 1 | 4 | 3 | 12 | 19 | -7 | 7 | Out |
| 26 | Sheriff | 8 | 2 | 1 | 5 | 11 | 24 | -13 | 7 | Out |
| 27 | Dinamo Zagreb | 8 | 2 | 1 | 5 | 11 | 26 | -15 | 7 | Out |
| 28 | Banik Ostrava | 8 | 2 | 1 | 5 | 11 | 28 | -17 | 7 | Out |
| 29 | AZ Alkmaar | 8 | 1 | 3 | 4 | 9 | 17 | -8 | 6 | Out |
| 30 | Slovan Bratislava | 8 | 1 | 2 | 5 | 7 | 16 | -9 | 5 | Out |
| 31 | Bayern Munich | 8 | 1 | 2 | 5 | 10 | 20 | -10 | 5 | Out |
| 32 | Atletico Madrid | 8 | 1 | 2 | 5 | 10 | 21 | -11 | 5 | Out |
| 33 | Inter Milan | 8 | 1 | 1 | 6 | 7 | 19 | -12 | 4 | Out |
| 34 | Club Brugge | 8 | 1 | 1 | 6 | 6 | 24 | -18 | 4 | Out |
| 35 | Copenhagen | 8 | 0 | 2 | 6 | 6 | 14 | -8 | 2 | Out |
| 36 | LASK | 8 | 0 | 2 | 6 | 7 | 18 | -11 | 2 | Out |