| Round of 16 — Direct Qualification | ||||||||||
| 1 | Arsenal | 8 | 8 | 0 | 0 | 29 | 4 | +25 | 24 | Direct |
| 2 | Real Madrid | 8 | 7 | 1 | 0 | 19 | 5 | +14 | 22 | Direct |
| 3 | Benfica | 8 | 7 | 0 | 1 | 25 | 3 | +22 | 21 | Direct |
| 4 | Paris SG | 8 | 7 | 0 | 1 | 22 | 6 | +16 | 21 | Direct |
| 5 | Barcelona | 8 | 7 | 0 | 1 | 29 | 15 | +14 | 21 | Direct |
| 6 | RB Leipzig | 8 | 6 | 1 | 1 | 21 | 6 | +15 | 19 | Direct |
| 7 | Liverpool | 8 | 6 | 0 | 2 | 23 | 7 | +16 | 18 | Direct |
| 8 | Fenerbahce | 8 | 6 | 0 | 2 | 22 | 15 | +7 | 18 | Direct |
| Knockout Playoff Round | ||||||||||
| 9 | Juventus | 8 | 6 | 0 | 2 | 19 | 14 | +5 | 18 | Playoff |
| 10 | Celtic | 8 | 5 | 2 | 1 | 16 | 10 | +6 | 17 | Playoff |
| 11 | Chelsea | 8 | 4 | 2 | 2 | 16 | 6 | +10 | 14 | Playoff |
| 12 | Galatasaray | 8 | 4 | 2 | 2 | 14 | 10 | +4 | 14 | Playoff |
| 13 | Porto | 8 | 4 | 1 | 3 | 16 | 15 | +1 | 13 | Playoff |
| 14 | Ajax | 8 | 4 | 1 | 3 | 18 | 18 | 0 | 13 | Playoff |
| 15 | Olympiacos | 8 | 4 | 0 | 4 | 16 | 14 | +2 | 12 | Playoff |
| 16 | Genk | 8 | 3 | 2 | 3 | 12 | 11 | +1 | 11 | Playoff |
| 17 | Red Bull Salzburg | 8 | 3 | 2 | 3 | 14 | 14 | 0 | 11 | Playoff |
| 18 | AC Milan | 8 | 3 | 2 | 3 | 15 | 17 | -2 | 11 | Playoff |
| 19 | Atletico Madrid | 8 | 3 | 1 | 4 | 13 | 15 | -2 | 10 | Playoff |
| 20 | Inter Milan | 8 | 3 | 1 | 4 | 13 | 15 | -2 | 10 | Playoff |
| 21 | Borussia Dortmund | 8 | 3 | 1 | 4 | 11 | 14 | -3 | 10 | Playoff |
| 22 | Brondby | 8 | 2 | 2 | 4 | 16 | 15 | +1 | 8 | Playoff |
| 23 | Young Boys | 8 | 2 | 2 | 4 | 13 | 19 | -6 | 8 | Playoff |
| 24 | Slovan Bratislava | 8 | 2 | 2 | 4 | 13 | 21 | -8 | 8 | Playoff |
| Eliminated | ||||||||||
| 25 | Sturm Graz | 8 | 2 | 1 | 5 | 9 | 19 | -10 | 7 | Out |
| 26 | Sheriff | 8 | 1 | 3 | 4 | 14 | 16 | -2 | 6 | Out |
| 27 | Copenhagen | 8 | 2 | 0 | 6 | 11 | 17 | -6 | 6 | Out |
| 28 | Shakhtar Donetsk | 8 | 1 | 3 | 4 | 15 | 23 | -8 | 6 | Out |
| 29 | Trabzonspor | 8 | 1 | 2 | 5 | 7 | 18 | -11 | 5 | Out |
| 30 | Bayern Munich | 8 | 1 | 2 | 5 | 9 | 22 | -13 | 5 | Out |
| 31 | Dinamo Zagreb | 8 | 1 | 2 | 5 | 7 | 20 | -13 | 5 | Out |
| 32 | PSV Eindhoven | 8 | 1 | 2 | 5 | 10 | 24 | -14 | 5 | Out |
| 33 | Club Brugge | 8 | 1 | 1 | 6 | 7 | 19 | -12 | 4 | Out |
| 34 | PAOK | 8 | 1 | 1 | 6 | 10 | 30 | -20 | 4 | Out |
| 35 | Manchester City | 8 | 1 | 0 | 7 | 6 | 20 | -14 | 3 | Out |
| 36 | Besiktas | 8 | 0 | 2 | 6 | 5 | 18 | -13 | 2 | Out |