| Round of 16 — Direct Qualification | ||||||||||
| 1 | Barcelona | 8 | 7 | 1 | 0 | 23 | 4 | +19 | 22 | Direct |
| 2 | Chelsea | 8 | 7 | 0 | 1 | 26 | 8 | +18 | 21 | Direct |
| 3 | Juventus | 8 | 7 | 0 | 1 | 23 | 8 | +15 | 21 | Direct |
| 4 | Arsenal | 8 | 6 | 2 | 0 | 27 | 3 | +24 | 20 | Direct |
| 5 | Liverpool | 8 | 6 | 1 | 1 | 20 | 7 | +13 | 19 | Direct |
| 6 | Genk | 8 | 6 | 0 | 2 | 20 | 13 | +7 | 18 | Direct |
| 7 | Galatasaray | 8 | 6 | 0 | 2 | 16 | 9 | +7 | 18 | Direct |
| 8 | Olympiacos | 8 | 4 | 3 | 1 | 21 | 9 | +12 | 15 | Direct |
| Knockout Playoff Round | ||||||||||
| 9 | Benfica | 8 | 4 | 2 | 2 | 18 | 6 | +12 | 14 | Playoff |
| 10 | Real Madrid | 8 | 4 | 2 | 2 | 14 | 9 | +5 | 14 | Playoff |
| 11 | Celtic | 8 | 4 | 2 | 2 | 15 | 11 | +4 | 14 | Playoff |
| 12 | RB Leipzig | 8 | 4 | 2 | 2 | 14 | 14 | 0 | 14 | Playoff |
| 13 | Shakhtar Donetsk | 8 | 4 | 1 | 3 | 19 | 12 | +7 | 13 | Playoff |
| 14 | Fenerbahce | 8 | 4 | 1 | 3 | 16 | 12 | +4 | 13 | Playoff |
| 15 | Paris SG | 8 | 4 | 1 | 3 | 10 | 9 | +1 | 13 | Playoff |
| 16 | Standard Liege | 8 | 3 | 3 | 2 | 13 | 8 | +5 | 12 | Playoff |
| 17 | Porto | 8 | 4 | 0 | 4 | 14 | 11 | +3 | 12 | Playoff |
| 18 | Ajax | 8 | 3 | 2 | 3 | 18 | 15 | +3 | 11 | Playoff |
| 19 | Basel | 8 | 3 | 1 | 4 | 14 | 13 | +1 | 10 | Playoff |
| 20 | Manchester City | 8 | 3 | 1 | 4 | 23 | 25 | -2 | 10 | Playoff |
| 21 | AZ Alkmaar | 8 | 3 | 1 | 4 | 14 | 19 | -5 | 10 | Playoff |
| 22 | Atletico Madrid | 8 | 3 | 1 | 4 | 10 | 15 | -5 | 10 | Playoff |
| 23 | Borussia Dortmund | 8 | 3 | 0 | 5 | 16 | 19 | -3 | 9 | Playoff |
| 24 | Ferencvaros | 8 | 3 | 0 | 5 | 12 | 21 | -9 | 9 | Playoff |
| Eliminated | ||||||||||
| 25 | Club Brugge | 8 | 2 | 2 | 4 | 11 | 14 | -3 | 8 | Out |
| 26 | Austria Wien | 8 | 2 | 2 | 4 | 13 | 21 | -8 | 8 | Out |
| 27 | Midtjylland | 8 | 2 | 1 | 5 | 15 | 22 | -7 | 7 | Out |
| 28 | Gent | 8 | 2 | 1 | 5 | 10 | 21 | -11 | 7 | Out |
| 29 | Bayern Munich | 8 | 2 | 1 | 5 | 7 | 20 | -13 | 7 | Out |
| 30 | Young Boys | 8 | 2 | 0 | 6 | 12 | 19 | -7 | 6 | Out |
| 31 | Red Bull Salzburg | 8 | 2 | 0 | 6 | 5 | 17 | -12 | 6 | Out |
| 32 | AC Milan | 8 | 1 | 2 | 5 | 9 | 17 | -8 | 5 | Out |
| 33 | PSV Eindhoven | 8 | 1 | 2 | 5 | 5 | 18 | -13 | 5 | Out |
| 34 | Anderlecht | 8 | 1 | 1 | 6 | 10 | 24 | -14 | 4 | Out |
| 35 | Dinamo Zagreb | 8 | 1 | 1 | 6 | 8 | 26 | -18 | 4 | Out |
| 36 | Inter Milan | 8 | 1 | 0 | 7 | 6 | 28 | -22 | 3 | Out |