| Round of 16 — Direct Qualification | ||||||||||
| 1 | Barcelona | 8 | 8 | 0 | 0 | 19 | 6 | +13 | 24 | Direct |
| 2 | Chelsea | 8 | 7 | 1 | 0 | 30 | 3 | +27 | 22 | Direct |
| 3 | Liverpool | 8 | 7 | 0 | 1 | 27 | 10 | +17 | 21 | Direct |
| 4 | Benfica | 8 | 7 | 0 | 1 | 21 | 6 | +15 | 21 | Direct |
| 5 | Paris SG | 8 | 6 | 1 | 1 | 17 | 7 | +10 | 19 | Direct |
| 6 | Juventus | 8 | 6 | 0 | 2 | 26 | 9 | +17 | 18 | Direct |
| 7 | Genk | 8 | 5 | 1 | 2 | 26 | 14 | +12 | 16 | Direct |
| 8 | Arsenal | 8 | 5 | 1 | 2 | 19 | 13 | +6 | 16 | Direct |
| Knockout Playoff Round | ||||||||||
| 9 | RB Leipzig | 8 | 5 | 0 | 3 | 15 | 10 | +5 | 15 | Playoff |
| 10 | Real Madrid | 8 | 4 | 3 | 1 | 18 | 14 | +4 | 15 | Playoff |
| 11 | Ajax | 8 | 4 | 2 | 2 | 14 | 15 | -1 | 14 | Playoff |
| 12 | Porto | 8 | 3 | 4 | 1 | 16 | 8 | +8 | 13 | Playoff |
| 13 | Olympiacos | 8 | 4 | 1 | 3 | 14 | 13 | +1 | 13 | Playoff |
| 14 | Dinamo Zagreb | 8 | 4 | 1 | 3 | 18 | 18 | 0 | 13 | Playoff |
| 15 | Red Bull Salzburg | 8 | 3 | 3 | 2 | 14 | 18 | -4 | 12 | Playoff |
| 16 | Basel | 8 | 3 | 2 | 3 | 17 | 13 | +4 | 11 | Playoff |
| 17 | Galatasaray | 8 | 3 | 1 | 4 | 19 | 12 | +7 | 10 | Playoff |
| 18 | Fenerbahce | 8 | 3 | 1 | 4 | 18 | 18 | 0 | 10 | Playoff |
| 19 | Cercle Brugge | 8 | 3 | 1 | 4 | 12 | 13 | -1 | 10 | Playoff |
| 20 | Brondby | 8 | 2 | 3 | 3 | 13 | 16 | -3 | 9 | Playoff |
| 21 | Celtic | 8 | 2 | 3 | 3 | 11 | 14 | -3 | 9 | Playoff |
| 22 | Shakhtar Donetsk | 8 | 3 | 0 | 5 | 10 | 15 | -5 | 9 | Playoff |
| 23 | Sturm Graz | 8 | 3 | 0 | 5 | 9 | 18 | -9 | 9 | Playoff |
| 24 | Manchester City | 8 | 2 | 2 | 4 | 18 | 22 | -4 | 8 | Playoff |
| Eliminated | ||||||||||
| 25 | Club Brugge | 8 | 2 | 2 | 4 | 10 | 17 | -7 | 8 | Out |
| 26 | Austria Wien | 8 | 2 | 2 | 4 | 11 | 21 | -10 | 8 | Out |
| 27 | CSKA Sofia | 8 | 2 | 2 | 4 | 8 | 19 | -11 | 8 | Out |
| 28 | PSV Eindhoven | 8 | 2 | 1 | 5 | 13 | 19 | -6 | 7 | Out |
| 29 | Atletico Madrid | 8 | 2 | 1 | 5 | 7 | 13 | -6 | 7 | Out |
| 30 | Young Boys | 8 | 2 | 1 | 5 | 11 | 22 | -11 | 7 | Out |
| 31 | Bayern Munich | 8 | 1 | 3 | 4 | 16 | 20 | -4 | 6 | Out |
| 32 | Inter Milan | 8 | 1 | 3 | 4 | 7 | 11 | -4 | 6 | Out |
| 33 | Standard Liege | 8 | 2 | 0 | 6 | 10 | 30 | -20 | 6 | Out |
| 34 | AC Milan | 8 | 1 | 1 | 6 | 11 | 26 | -15 | 4 | Out |
| 35 | AZ Alkmaar | 8 | 0 | 2 | 6 | 7 | 15 | -8 | 2 | Out |
| 36 | Borussia Dortmund | 8 | 0 | 1 | 7 | 5 | 19 | -14 | 1 | Out |