| Round of 16 — Direct Qualification | ||||||||||
| 1 | Liverpool | 8 | 7 | 1 | 0 | 23 | 4 | +19 | 22 | Direct |
| 2 | Paris SG | 8 | 7 | 1 | 0 | 23 | 9 | +14 | 22 | Direct |
| 3 | Barcelona | 8 | 7 | 0 | 1 | 28 | 6 | +22 | 21 | Direct |
| 4 | Arsenal | 8 | 7 | 0 | 1 | 25 | 9 | +16 | 21 | Direct |
| 5 | Galatasaray | 8 | 7 | 0 | 1 | 20 | 7 | +13 | 21 | Direct |
| 6 | Real Madrid | 8 | 6 | 1 | 1 | 20 | 6 | +14 | 19 | Direct |
| 7 | Chelsea | 8 | 5 | 3 | 0 | 16 | 6 | +10 | 18 | Direct |
| 8 | Ajax | 8 | 6 | 0 | 2 | 19 | 10 | +9 | 18 | Direct |
| Knockout Playoff Round | ||||||||||
| 9 | Fenerbahce | 8 | 5 | 2 | 1 | 13 | 7 | +6 | 17 | Playoff |
| 10 | Juventus | 8 | 5 | 1 | 2 | 16 | 9 | +7 | 16 | Playoff |
| 11 | Genk | 8 | 5 | 0 | 3 | 18 | 9 | +9 | 15 | Playoff |
| 12 | Olympiacos | 8 | 4 | 2 | 2 | 23 | 10 | +13 | 14 | Playoff |
| 13 | Benfica | 8 | 4 | 2 | 2 | 22 | 10 | +12 | 14 | Playoff |
| 14 | Dinamo Zagreb | 8 | 4 | 2 | 2 | 10 | 12 | -2 | 14 | Playoff |
| 15 | Club Brugge | 8 | 4 | 1 | 3 | 12 | 13 | -1 | 13 | Playoff |
| 16 | Porto | 8 | 3 | 2 | 3 | 16 | 10 | +6 | 11 | Playoff |
| 17 | Standard Liege | 8 | 2 | 4 | 2 | 14 | 14 | 0 | 10 | Playoff |
| 18 | RB Leipzig | 8 | 3 | 1 | 4 | 13 | 13 | 0 | 10 | Playoff |
| 19 | Bayern Munich | 8 | 2 | 3 | 3 | 14 | 18 | -4 | 9 | Playoff |
| 20 | PSV Eindhoven | 8 | 3 | 0 | 5 | 8 | 14 | -6 | 9 | Playoff |
| 21 | Atletico Madrid | 8 | 1 | 5 | 2 | 14 | 14 | 0 | 8 | Playoff |
| 22 | CSKA Sofia | 8 | 2 | 2 | 4 | 14 | 14 | 0 | 8 | Playoff |
| 23 | Birkirkara | 8 | 2 | 2 | 4 | 8 | 17 | -9 | 8 | Playoff |
| 24 | Manchester City | 8 | 1 | 4 | 3 | 7 | 12 | -5 | 7 | Playoff |
| Eliminated | ||||||||||
| 25 | Red Bull Salzburg | 8 | 2 | 1 | 5 | 11 | 19 | -8 | 7 | Out |
| 26 | Celtic | 8 | 2 | 1 | 5 | 10 | 20 | -10 | 7 | Out |
| 27 | Sturm Graz | 8 | 2 | 1 | 5 | 6 | 17 | -11 | 7 | Out |
| 28 | Molde | 8 | 1 | 3 | 4 | 9 | 15 | -6 | 6 | Out |
| 29 | Shakhtar Donetsk | 8 | 2 | 0 | 6 | 12 | 31 | -19 | 6 | Out |
| 30 | Legia Warsaw | 8 | 1 | 2 | 5 | 11 | 19 | -8 | 5 | Out |
| 31 | Borussia Dortmund | 8 | 1 | 2 | 5 | 8 | 19 | -11 | 5 | Out |
| 32 | Copenhagen | 8 | 0 | 4 | 4 | 10 | 16 | -6 | 4 | Out |
| 33 | Twente | 8 | 1 | 1 | 6 | 11 | 19 | -8 | 4 | Out |
| 34 | Cercle Brugge | 8 | 1 | 1 | 6 | 9 | 25 | -16 | 4 | Out |
| 35 | Inter Milan | 8 | 1 | 0 | 7 | 7 | 23 | -16 | 3 | Out |
| 36 | AC Milan | 8 | 0 | 1 | 7 | 7 | 31 | -24 | 1 | Out |