| Round of 16 — Direct Qualification | ||||||||||
| 1 | Barcelona | 8 | 8 | 0 | 0 | 25 | 2 | +23 | 24 | Direct |
| 2 | Liverpool | 8 | 7 | 0 | 1 | 34 | 8 | +26 | 21 | Direct |
| 3 | Chelsea | 8 | 7 | 0 | 1 | 20 | 4 | +16 | 21 | Direct |
| 4 | Porto | 8 | 6 | 2 | 0 | 25 | 9 | +16 | 20 | Direct |
| 5 | Real Madrid | 8 | 6 | 2 | 0 | 22 | 6 | +16 | 20 | Direct |
| 6 | Paris SG | 8 | 6 | 1 | 1 | 24 | 7 | +17 | 19 | Direct |
| 7 | Juventus | 8 | 6 | 1 | 1 | 17 | 7 | +10 | 19 | Direct |
| 8 | Olympiacos | 8 | 6 | 0 | 2 | 23 | 15 | +8 | 18 | Direct |
| Knockout Playoff Round | ||||||||||
| 9 | Celtic | 8 | 5 | 2 | 1 | 20 | 14 | +6 | 17 | Playoff |
| 10 | Arsenal | 8 | 5 | 1 | 2 | 21 | 10 | +11 | 16 | Playoff |
| 11 | Dinamo Zagreb | 8 | 5 | 1 | 2 | 13 | 10 | +3 | 16 | Playoff |
| 12 | Club Brugge | 8 | 5 | 0 | 3 | 21 | 10 | +11 | 15 | Playoff |
| 13 | Benfica | 8 | 4 | 2 | 2 | 17 | 7 | +10 | 14 | Playoff |
| 14 | Sparta Prague | 8 | 4 | 1 | 3 | 12 | 9 | +3 | 13 | Playoff |
| 15 | Ajax | 8 | 4 | 1 | 3 | 12 | 13 | -1 | 13 | Playoff |
| 16 | Rangers | 8 | 3 | 3 | 2 | 19 | 17 | +2 | 12 | Playoff |
| 17 | Ludogorets | 8 | 3 | 2 | 3 | 9 | 13 | -4 | 11 | Playoff |
| 18 | Red Bull Salzburg | 8 | 3 | 1 | 4 | 18 | 20 | -2 | 10 | Playoff |
| 19 | RB Leipzig | 8 | 1 | 6 | 1 | 11 | 8 | +3 | 9 | Playoff |
| 20 | Genk | 8 | 3 | 0 | 5 | 13 | 14 | -1 | 9 | Playoff |
| 21 | Fenerbahce | 8 | 2 | 3 | 3 | 10 | 15 | -5 | 9 | Playoff |
| 22 | Atletico Madrid | 8 | 2 | 2 | 4 | 17 | 24 | -7 | 8 | Playoff |
| 23 | Astana | 8 | 2 | 2 | 4 | 10 | 17 | -7 | 8 | Playoff |
| 24 | AZ Alkmaar | 8 | 2 | 2 | 4 | 9 | 18 | -9 | 8 | Playoff |
| Eliminated | ||||||||||
| 25 | Wisla Krakow | 8 | 2 | 1 | 5 | 12 | 14 | -2 | 7 | Out |
| 26 | Bayern Munich | 8 | 2 | 1 | 5 | 11 | 16 | -5 | 7 | Out |
| 27 | Twente | 8 | 2 | 1 | 5 | 8 | 17 | -9 | 7 | Out |
| 28 | Shakhtar Donetsk | 8 | 2 | 1 | 5 | 11 | 22 | -11 | 7 | Out |
| 29 | Manchester City | 8 | 1 | 3 | 4 | 8 | 17 | -9 | 6 | Out |
| 30 | Inter Milan | 8 | 1 | 2 | 5 | 9 | 16 | -7 | 5 | Out |
| 31 | Galatasaray | 8 | 1 | 2 | 5 | 9 | 17 | -8 | 5 | Out |
| 32 | Panathinaikos | 8 | 1 | 1 | 6 | 7 | 23 | -16 | 4 | Out |
| 33 | Cercle Brugge | 8 | 1 | 0 | 7 | 7 | 28 | -21 | 3 | Out |
| 34 | AC Milan | 8 | 1 | 0 | 7 | 5 | 26 | -21 | 3 | Out |
| 35 | PSV Eindhoven | 8 | 0 | 2 | 6 | 5 | 25 | -20 | 2 | Out |
| 36 | Borussia Dortmund | 8 | 0 | 1 | 7 | 6 | 22 | -16 | 1 | Out |